Primary Malignant Melanoma of Uterine Cervix with Disseminated Involvement of Lower Genitourinary Tract

Introduction: Primary malignant melanomas (MM) of the female urogenital tract are extremely rare and aggressive neoplasms. The majority these neoplasms occur in postmenopausal women, originate from vulva vagina, involvement uterus, cervix, ovary is exceedingly uncommon. Case Presentation: We presented a patient with MM uterine first diagnosed punch biopsy lesion, which was distributed cervical mass to vestibule labia minor. She underwent anterior pelvic exenteration. Pathology evaluation revealed primary cervix FIGO stage III. received adjuvant treatment radiation immunotherapy. On her fallow up 1 year after disease diagnosis, she still alive without evidence distant metastasis. Conclusions: When feasible, exenteration offers appropriate initial management MM.